Poly-Histine CS: Uses, Side Effects & Dosage
Poly-Histine CS is a combination medication used for temporary relief of symptoms associated with the common cold, hay fever, and upper respiratory allergies. It helps relieve cough, sneezing, runny nose, itchy and watery eyes, and nasal congestion.
Table of Contents
Introduction to Poly-Histine CS
Poly-Histine CS is an over-the-counter (OTC) combination medication containing doxylamine (an antihistamine) and phenylephrine (a decongestant). It is formulated to provide temporary relief from symptoms associated with the common cold, hay fever, and other upper respiratory allergies. Poly-Histine CS is available in various forms, including liquid, capsules, and long-acting capsules, making it convenient for different age groups and preferences.
Uses and Indications
Poly-Histine CS is commonly used for the following purposes:
- Treatment of common cold symptoms, such as cough, sneezing, runny nose, and nasal congestion.
- Relief from hay fever and upper respiratory allergies, including itchy and watery eyes, nasal congestion, and sneezing.
- Management of flu symptoms, such as body aches, fever, and respiratory discomfort.
- Relief from sinusitis and sinus congestion.
It is important to note that Poly-Histine CS is intended for temporary relief of these symptoms and should not be used as a long-term treatment.
Source: National Center for Biotechnology Information (NCBI)
Composition and Active Ingredients
Poly-Histine CS contains two active ingredients:
- Doxylamine : An antihistamine that helps relieve symptoms like sneezing, itchy and watery eyes, and runny nose.
- Phenylephrine : A decongestant that helps reduce nasal congestion and sinus pressure.
The combination of these ingredients makes Poly-Histine CS effective in addressing multiple symptoms associated with the common cold, hay fever, and upper respiratory allergies.
Source: Drugs.com
Mechanism of Action
Poly-Histine CS works by targeting two different mechanisms in the body:
- Antihistamine Action ( Doxylamine): Doxylamine blocks the action of histamine, a natural chemical in the body that causes allergy symptoms like sneezing, itching, and runny nose. By blocking histamine, doxylamine helps alleviate these symptoms.
- Decongestant Action ( Phenylephrine): Phenylephrine is a decongestant that constricts blood vessels in the nasal passages, reducing inflammation and swelling. This action helps relieve nasal congestion and sinus pressure.
The combination of these two mechanisms provides comprehensive relief from a range of cold and allergy symptoms.
Source: Mayo Clinic
Available Forms and Dosage
Poly-Histine CS is available in the following forms:
- Liquid Formulations: Available as a syrup or liquid-filled capsules, suitable for both adults and children.
- Capsules: Regular-release capsules for adults and children over 12 years old.
- Long Acting Capsules: Extended-release capsules for adults and children over 12 years old, providing longer-lasting relief.
The recommended dosage varies based on age, form, and individual circumstances. It is essential to follow the instructions on the product label or consult with a healthcare professional for proper dosing.
Source: WebMD
Side Effects
Like any medication, Poly-Histine CS may cause side effects in some individuals. Common side effects include:
- Drowsiness or dizziness
- Dry mouth
- Headache
- Nausea or vomiting
- Insomnia
Severe side effects, although rare, may include:
- Rapid or irregular heartbeat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Seizures
It is important to seek medical attention if you experience any severe side effects or if the symptoms persist or worsen.
Source: RxList
Interactions with Other Medications
Poly-Histine CS may interact with certain medications, which can affect its effectiveness or increase the risk of side effects. Some potential interactions include:
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
- Anticholinergic drugs
- Blood pressure medications
It is important to inform your healthcare provider about all the medications you are taking, including over-the-counter drugs, supplements, and herbal products, to avoid potential interactions.
Source: Drugs.com
Contraindications and Precautions
Poly-Histine CS should be used with caution in certa in situations and may be contraindicated in others. Some of the contraindications and precautions include:
- Glaucoma or increased intraocular pressure
- Urinary retention or bladder obstruction
- Severe cardiovascular disorders
- Thyroid disorders
- Pregnancy and breastfeeding (consult a healthcare provider)
It is also important to exercise caution when using Poly-Histine CS in children, as it may cause excitability or paradoxical reactions.
Source: Drugs.com
Comparison with Other Medications
Poly-Histine CS is part of a family of combination medications that also includes Poly-Hist DM and Poly-Hist PD. These medications share some similarities but also have differences in their compositions and intended uses:
- Poly-Hist DM: Contains doxylamine (antihistamine) and dextromethorphan (cough suppressant), used for relief of cough and cold symptoms.
- Poly-Hist PD: Contains phenylephrine (decongestant) and pyrilamine (antihistamine), used for relief of nasal congestion and allergy symptoms.
Compared to these alternatives, Poly-Histine CS offers a unique combination of an antihistamine and a decongestant, making it suitable for addressing a broader range of cold and allergy symptoms.
Source: Drugs.com
Usage Guidelines and Warnings
To ensure safe and effective use of Poly-Histine CS, it is important to follow these guidelines and warnings:
- Read and follow the instructions on the product label or as directed by a healthcare professional.
- Do not exceed the recommended dosage or duration of use.
- Do not use Poly-Histine CS if you have certain medical conditions or are taking certain medications without consulting a healthcare provider.
- Avoid alcohol consumption while taking Poly-Histine CS, as it may increase drowsiness and impairment.
- Use caution when operating heavy machinery or engaging in activities that require alertness, as Poly-Histine CS may cause drowsiness.
- Seek medical attention if symptoms persist or worsen, or if you experience any severe side effects.
Remember, Poly-Histine CS is intended for temporary relief of symptoms and should not be used as a long-term treatment.
Source: FDA
